SELPHYL PRFM treatments take platelet-rich plasma (PRP) a step further, offering a more stable and longer-lasting solution for skin and tissue rejuvenation. Platelet-rich fibrin matrix (PRFM) extends the release of growth factors and has a more sustained effect. This controlled release helps support collagen production and tissue repair.
We use the SELPHYL system at Pure Bella Aesthetic Boutique to prepare PRFM in a way that reduces variability and enhances treatment outcomes. With our approach in Newnan, GA, you can benefit from a more predictable response that supports smoother, healthier-looking skin with fewer treatments.
What Is SELPHYL PRFM?
SELPHYL PRFM is an advanced type of platelet-rich plasma (PRP) therapy that uses your body’s platelets and fibrin to promote tissue regeneration and collagen production. PRFM uses growth factors to enhance the natural healing process. When injected or used topically, the resulting product allows for a natural approach to skin rejuvenation.
Exploring the Differences Between PRP and PRFM
Traditional PRP
Platelet-rich plasma (PRP) treatments rely on the natural healing properties of platelets to stimulate collagen production and tissue repair. The process involves drawing blood, separating platelets through centrifugation, and injecting the concentrated plasma back into the skin or treatment area. Once injected, PRP begins breaking down quickly, which limits the duration of growth factor release. This short activity window may require more frequent treatments to maintain results.
PRFM
Platelet-rich fibrin matrix (PRFM) builds on PRP by adding a fibrin scaffold that stabilizes platelets and extends their release of growth factors. This structure slows degradation and allows for a more sustained effect with fewer treatments. With PRFM, patients receive a longer-lasting and more consistent regenerative response compared to traditional PRP.
A Closer Look at the SELPHYL System
The PRP to PRFM conversion achieved through the SELPHYL system removes red and white blood cells and other elements for a purer product. The PRFM forms a fibrin scaffold, which supports sustained release of growth factors over several days and promotes tissue regeneration and healing.
A benefit of the SELPHYL system is its closed design, which minimizes contamination risks and provides consistent results. The standardized process reduces variability between treatments and provides more predictable outcomes for patients.
How Does SELPHYL PRFM Work?
- Blood Draw: A small sample of blood is taken from the patient using a vacuum-sealed collection tube containing a separation gel. This step ensures that the sample remains uncontaminated and properly prepared for processing.
- Centrifugation: The collected blood is placed in a centrifuge and spun for six minutes, separating the plasma and platelets from red and white blood cells. This step isolates the beneficial components needed for tissue regeneration.
- Formation of PRFM: The plasma and platelet suspension is transferred to a second tube containing calcium chloride, triggering fibrin polymerization. Over the next 20 minutes, the PRP transforms into PRFM, creating a matrix that stabilizes platelets and extends their activity.
Conditions That Can Be Treated With SELPHYL PRFM
Skin Rejuvenation
Achieving smoother, healthier-looking skin often requires more than surface treatments and over-the-counter products. PRFM injections go deeper, supplying growth factors that gradually improve skin texture and elasticity. Extending the activity of platelets helps restore a fresher, more even complexion.
Volume Loss and Facial Contouring
Facial structure changes with age, which often leads to hollowing in key areas like the cheeks and temples. Rather than simply filling these spaces, PRFM works with the body to rebuild natural volume. As new collagen forms, facial contours become more defined for subtle, natural-looking enhancement.
Wrinkle Treatment
Instead of temporarily plumping the skin, PRFM takes a regenerative approach to softening wrinkles. The fibrin matrix holds platelets in place and allows them to release growth factors that gradually support tissue renewal. This process improves skin integrity from within and helps wrinkles appear less pronounced over time.
Under-Eye Rejuvenation
The under-eye area is delicate, making it difficult to treat effectively with traditional methods. We love SELPHYL PRFM because it provides a more natural solution by reinforcing the skin’s structure and improving circulation in the treated area. You may notice gradual improvements in hydration, resilience, and overall brightness beneath the eyes.
Acne Scars
Scarred skin tends to be uneven and firm due to improper collagen formation during healing. This can result in pitted areas across the face, or sometimes in raised scars. PRFM helps remodel this tissue by stimulating the skin’s repair mechanisms. As collagen production increases, pitted scars begin to soften, and scar tissue can begin to break down.
Lip and Perioral Rejuvenation
Aging can lead to subtle changes in the lips and surrounding skin, causing fine lines and volume loss. PRFM injections encourage natural regeneration, which can enhance lip definition and soften vertical lines when injected into the area. The gradual nature of the treatment allows for results that blend seamlessly with the natural contours of the face.
Neck and Décolletage Revitalization
The skin on the neck and chest is often exposed to environmental stressors and can be one of the first areas to show signs of aging. If you have noticed sagging, sun damage, or a crepey texture in this area, we can strengthen the skin’s support structure. Over time, the skin appears firmer and more even-toned.
Other Uses
PRFM is also sometimes used in hair restoration, where it supports follicle health and encourages new growth. It can also be used for joint pain management by assisting with tissue repair and inflammation control. Its regenerative properties make it a versatile option across multiple medical and aesthetic applications.
What Are the Benefits of SELPHYL PRFM?
Natural and Autologous Treatment
SELPHYL PRFM is derived from the patient’s blood.. Because it works with the body’s natural healing processes, the treatment integrates seamlessly with existing tissue. This reduces the risk of adverse reactions while promoting gradual, natural-looking improvements.
Minimal Downtime
Most patients can return to daily activities shortly after treatment without needing recovery time. The injection process itself is quick and a convenient option for those with busy schedules.
Treatment Versatility
PRFM is not limited to one type of cosmetic enhancement. It can be used to improve skin quality, restore volume, and soften wrinkles anywhere. We can adjust the treatment to suit your situation,
Your Pre-Treatment Consultation
Before moving forward with PRFM injections, we take time to assess your skin, discuss your concerns, and determine if this treatment aligns with your goals. We will review your medical history to make sure it’s the right approach. We’ll also go over what to expect during and after the treatment so you feel fully prepared.
Post-Treatment Care
There’s no extensive recovery time, but we do recommend avoiding excessive sun exposure, strenuous exercise, and certain skincare products for the first day or two. You might experience mild, temporary swelling or redness at the injection sites. Results develop gradually as your body responds to the growth factors, so improvements continue over the following weeks. If needed, we can discuss a follow-up plan to maintain and enhance your results.
A Few Common Questions About PRFM Treatments
Discomfort is minimal, and most patients tolerate the treatment well. We use a fine needle for injections, similar to those used for fillers or Botox®. If needed, we can apply a topical numbing cream beforehand to make the process more comfortable. Any tenderness at the injection site fades quickly, and most patients go about their day without any issues.
Since PRFM injections use your own blood, the risk of an allergic reaction is extremely low. The most common effects are mild swelling, redness, or slight bruising at the injection sites. We’ll go over any specific concerns during your consultation so you know exactly what to expect.
The number of treatments depends on the area being addressed and the results you’re looking for. Some patients see noticeable improvement after just one session, but most benefit from a series of two to three treatments spaced a few weeks apart. If we’re treating more advanced concerns like deep wrinkles or acne scars, additional sessions may be recommended. We’ll create a customized treatment plan based on your needs.
Results develop gradually as the PRFM stimulates collagen production and tissue regeneration. Some patients notice subtle changes within the first few weeks, but the most significant improvements typically appear over two to three months. Because the treatment enhances your skin’s natural repair process, the results continue to improve with time.
PRFM offers longer-lasting effects than traditional PRP because of its sustained release of growth factors. However, these results are different for every patient. Once the full effects are seen, you may notice improvements for many months after the treatment. Regular maintenance treatments and a proper skin care routine can help extend these benefits, and we can adjust your treatment plan as needed.
PRFM is a good option for patients looking to improve skin texture, restore lost volume, or reduce the appearance of fine lines and scars using their body’s natural healing process. It works well for those who prefer gradual, long-lasting results over immediate but temporary solutions. Since PRFM is derived from the patient’s own blood, it is generally well-tolerated, but it may not be suitable for individuals with blood disorders, active infections, or certain autoimmune conditions. A consultation helps determine if this treatment aligns with your goals and medical history.
PRFM and dermal fillers both address volume loss and skin aging, but they work in different ways. Fillers add immediate volume using hyaluronic acid or other substances, while PRFM stimulates collagen production over time for gradual, longer-lasting improvements. The choice depends on the results you are looking for and other factors such as treatment longevity, aesthetic goals, and when you want to see your results.
Choosing Our Treatments in Newnan, GA
At Pure Bella Aesthetic Boutique, we bring experience and precision to every treatment we offer. Our founder, Brandilyn Johnson, is a nurse practitioner with over a decade of dermatology experience, specializing in both cosmetic and medical skin care. After moving to Newnan in 2020, she quickly became a trusted provider in the community, offering advanced treatments designed to support long-term skin health. In 2022, she expanded her passion for aesthetics by opening Pure Bella on the second floor of Tigerlilly, her locally owned boutique. Whether you’re exploring PRFM treatments, you want to explore our skin rejuvenation options, or you want to pet our Pure Bella mascot, Tucker the mini goldendoodle, we’re here to help in our welcoming, professional boutique setting.
Find Out More About the SELPHYL PRFM Treatment Process Today
PRFM offers a longer-lasting approach to skin rejuvenation by supporting natural collagen production and tissue repair. By gradually releasing growth factors, it provides consistent results that traditional PRP treatments may not achieve. At Pure Bella Aesthetic Boutique in Newnan, GA, treatments are performed using the SELPHYL system to refine and stabilize platelet-rich plasma for optimal effectiveness. To learn more or schedule a consultation, call (770) 755-6610 or contact us through the online form. We are proud to serve all of the surrounding areas including Atlanta, Columbus, Peachtree City, Senoia, Fayetteville, Carrollton, LaGrange, Sharpsburg, Chattahoochee Hills, and more.